Actually, I say that mostly because I'm mad at the moment about its imaginary .Mac syncing. In general, I like Yojimbo for what I use it for (more on that in a sec) but its big selling point for me was .Mac syncing. In fact, .Mac's big selling point for me was Yojimbo syncing. I'm a person of what you might call "professorial" temperament (read: absent-minded as all hell) and manage my informational life between 2 computers, at work and at home. Having the same resources available on both ends is very important to me, which is why paying $100 just to have calendars and addresses always the same on both ends didn't seem altogether unreasonable to me. Keeping other important info, via Yojimbo, in constant sync would be a huge boon, if only it actually worked.

I've never once been able to sync my Yojimbo items between the two computers.

Other than that one (big) thing, Yojimbo has all the qualities that you'd want in a tag-n-drop brain substitute. Easy in, easy tagging, easy out. And reasonably pretty to look at.

Fwiw, I got on the tag-n-drop bandwagon about 6 months ago, and a mixed system is working well for me. For the most part, I dump everything into a few folders (for instance, documents for documents, "notes" for text files with information I'll want later, or want to be able to append via Quicksilver, etc) and use Hazel and Default Folder X to help enforce tagging practices. Yojimbo I use for special classes of items; mostly smallish things that I know for sure I'll need sooner or later, like account/registration/license/password kinds of things. There's no real reason I couldn't use my roll-your-own system for this stuff, and actually there is some redundancy (a good thing, I think) but the separation helps me adhere to good practices.

Based on my experience, I endorse a mixed hierarchical/tag-n-drop system. The problem with hierarchical systems is that they force you to make a bunch of decisions that you might regret later. But sometimes, these decisions are overwhelmingly obvious. Tag-n-Drop gets you free of this obligation, but using folder hierarchies where they're clearly indicated helps with visual/mental clutter and doesn't cost anything. For instance, in "Documents," I'm mostly wild-west open spaces, but I do have a couple of subfolders, like "webreceipts," because I've got a bunch of the goddam things, and I'll never want to look at them unless I need them, so why bother with the extra clutter if ever I need to browse the various and sundry other things in "Documents?"

As long as I'm writing the longest-ever 43f comment, let me also mention that for me, Path Finder has been essential to making this mixed system work: viewing lists of files while being able to preview their contents is the key.

I have a copy of DevonThink Personal, but I'll be damned if I can figure out what special thing it's supposed to do for me. If anybody has suggestions about that, I'm all ears.